There are five separately incorporated school systems:
Elk County Catholic School System- Elk County Catholic High School, St. Marys
- St. Leo School, Ridgway
- St. Marys Catholic Elementary School, St. Marys
- St. Marys Catholic Middle School, St. Marys
Villa Maria Cathedral Preparatory Catholic School System
Erie Catholic School System
- Blessed Sacrament School, Erie
- Our Lady of Peace School, Erie
- St. George School, Erie
- St. James School, Erie
- St. Jude School, Erie
- St. Luke School, Erie
DuBois Area Catholic Schools
- DuBois Central Catholic Elementary School, DuBois
- DuBois Central Catholic Middle School, DuBois
- DuBois Central Catholic High School, DuBois
Shenango Valley Catholic School System
- Kennedy Catholic High School, Hermitage
- Kennedy Catholic Middle School, Hermitage
- St. John Paul II Elementary School, Hermitage
One school system established as a non-profit association:
Venango Region Catholic School
There are 8 parish-based schools:
- Immaculate Conception School, Clarion
- St. Francis School, Clearfield
- St. Gregory School, North East
- St. Joseph School, Lucinda
- St. Joseph School, Warren
- St. Michael School, Greenville
- Ss. Cosmas and Damian School, Punxsutawney
- Seton Catholic School, Meadville